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Eating disorders could be observed at the start of the condition but are more obvious in the middle stage. The individual has problems swallowing and chokes frequently. Epileptic seizures can develop.. Alzheimer’s Disease in People who have Down syndrome – Symptoms In people who have Down syndrome, the first symptoms usually develop at age 50 years, and the condition is diagnosed by age 52 years usually. Death occurs at an average age of 60.11 years. The time from the first symptoms of Alzheimer’s disease to loss of life is normally about 9 years. The main symptoms are misunderstandings, disorientation, and wandering.